Crime and Justice Atlas

How Justice Is Served
Forensic Disciplines and Methods

DNA Profiling

Also Known As Genetic fingerprinting

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The identification of individuals through their genetic material, developed by Alec Jeffreys. It was first used to convict a criminal in the Colin Pitchfork case of 1988, and has since become a central technology for both conviction and exoneration.

Facts
What It Examines
Highly variable regions of the human genome, compared between a crime scene sample and a known sample to establish or exclude a common source with quantifiable statistical weight. 1
Formalized Year
1984 2
Sourced to the subject's own accountThe year Alec Jeffreys developed DNA fingerprinting at the University of Leicester.
Known Limitation
Partial, degraded or mixed samples from more than one contributor can reduce the statistical power of a match and complicate interpretation of the profile. 1
Cross-Tradition Connections

Associated With

CODIS, Criminal Justice Institutions

CODIS is the national database infrastructure built on DNA profiling.

Forensic serology historically preceded DNA profiling and now commonly serves as its preliminary screening step.

The database holds DNA profiles taken from individuals and crime scenes for identification and matching.

Cases Where Used

Amanda Knox Case, Landmark Cases

A court-ordered independent review found numerous basic errors in how the contested DNA evidence was gathered and analyzed.

Post-conviction DNA testing matched semen evidence to Matias Reyes rather than to the five originally convicted teenagers.

The first murder conviction obtained through DNA profiling.

Investigative genetic genealogy built on a public genealogy-database DNA match identified Joseph James DeAngelo in 2018.

DNA analysis of preserved evidence identified Gary Ridgway two decades after the murders.

DNA evidence from blood at the scene and on physical evidence was central to the prosecution case.

Post-conviction DNA testing that found no biological evidence linking the defendants to the crime scene was central to the Alford plea that freed them in 2011.

Pioneered By

Sources
1. Saferstein, Criminalistics: An Introduction to Forensic Science
Richard Saferstein, Pearson
2. Wikipedia: Alec Jeffreys
Wikipedia: Combined DNA Index System
Associated With: CODISView the Source
Wikipedia: Colin Pitchfork
Cases Where Used: Colin Pitchfork CaseView the Source
Wikipedia: Gary Ridgway
Cases Where Used: Green River Killer CaseView the Source
Wikipedia: Forensic Serology
Associated With: Forensic Serology, Opening definitionView the Source
Wikipedia: Murder of Meredith Kercher
Cases Where Used: Amanda Knox Case, DNA evidence review section
Quote, Cases Where Used: Amanda Knox Case, DNA evidence review section
no evidential trace of Kercher's DNA had been found on the alleged murder weapon
View the Source
Wikipedia: National DNA Database
Associated With: UK National DNA Database, Lead section
Quote, Associated With: UK National DNA Database, Lead section
The first national DNA database in the United Kingdom was established in April 1995, called National DNA Database (NDNAD).
View the Source
Wikipedia: Joseph James DeAngelo
Cases Where Used: Golden State Killer CaseView the Source
Wikipedia: O. J. Simpson murder case
Cases Where Used: O. J. Simpson Murder CaseView the Source
Wikipedia: Central Park Jogger Case
Cases Where Used: Central Park Jogger CaseView the Source
Wikipedia: West Memphis Three
Cases Where Used: West Memphis Three CaseView the Source
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